Google +
 
   
 

 

 

Stem Cell Tourism

Stem cell tourism is a new form of medical travel to purchase unproven stem cell-based therapies.  These unproven treatments hold significant risk for people.  Case in point, the German government recently shut down the XCell-Center because someone died as a result of the treatments they sold.  It is essential for people with SCI to be informed before they risk their lives on such therapies which have no scientific basis.  Below are some excellent educational resources.


European SCI Federation
Unproven Therapies

California Institute for Regenerative Medicine

Australian SCI Network

ISSCR Consumer Handbook

ASSC Information Handbook

NIH Stem Cell Information

Ethics of Stem Cell Research

Home > Research Research Participation > Experimental Treatments

 

EXPERIMENTAL TREATMENTS FOR SPINAL CORD INJURIES:
WHAT YOU SHOULD KNOW IF YOU ARE CONSIDERING PARTICIPATION IN A CLINICAL TRIAL

 

Increasingly, advances in spinal cord injury (SCI) research are finding their way into clinical practice. Many of these experimental therapies are currently undergoing clinical trials or are preparing to enter the clinical trial phase of their development. However, a number of experimental therapies, such as cellular transplants, are being introduced into clinical practice without a valid clinical trial program being completed, leaving their safety and efficacy untested. This is a great concern to researchers, clinicians, and most importantly people with SCI.

 

For people with SCI, their families, friends and caregivers, the decision to receive an experimental treatment or enter a clinical trial is a challenging one. To establish a set of guidelines for the design and conduct of valid clinical trials for SCI, an expert panel of researchers and doctors with extensive scientific and clinical experience in SCI was formed in 2004. The panel, supported through the ICCP (International Campaign for Cures for spinal cord injury Paralysis), developed a set of 4 papers outlining the guidelines for the conduct of SCI clinical trials, which were published in the Nature journal, Spinal Cord (see below). In addition to these peer-reviewed publications, the panel summarized these guidelines in an easy-to-read booklet.

 

 

As a member of the International Campaign for Cures of spinal cord injury Paralysis (ICCP), The Miami Project to Cure Paralysis supports the recently published position statement regarding the sale of unproven cellular therapies.

 

•It is unethical to charge people money for experimental interventions that have not been proven safe and effective by clinical trials conducted in a proper manner.

 

•Testimonials reported by people who have received a treatment, or by their family members, are not valid medical evidence.

 

•Proper control groups are needed to evaluate the placebo-effect; the people profiting financially from the treatment should not be measuring safety and efficacy, they are potentially biased by financial gain.

 

•There are significant risks associated with cell-based treatments. Cells cannot be taken out once they are put inside the body. Therefore, very thorough long-term follow-up should be provided at no cost to the participant.

 

•People who receive unproven cellular treatments will most likely be excluded from future scientifically valid clinical trials.

 

“We do not rule out the possibility that cellular therapies may improve function and quality of life for recipients and justify the risks, but insist that the onus is on the providers to deliver such proof from a valid clinical-trial program.” We believe that it is unethical to sell unproven therapies and we do not advice people with spinal cord injuries to participate in such treatment procedures. The complete ICCP statement was published in Spinal Cord (2009) 47: 713-714.

 

 

For people with spinal cord injury, their families, friends and caregivers:

 

Documents now available for download:

 

 

 

Experimental Treatments for Spinal Cord Injuries: What you should know if you are considering participation in a clinical trial  

40-page-guide (2.4MB)

 

 

 

 

 

 International Translations:
 
Spanish
 
Japanese
 
German
 
Chinese
 
French
 
Turkish


 

 

   

 

 For Scientific and Clinical Colleagues:  

 

Guidelines for:
The Conduct of Clinical Trials for Spinal Cord Injury

(As developed by: The International Campaign for the Cure of Spinal Cord Paralysis panel)

 

1. Spontaneous recovery after SCI and statistical power needed for therapeutic clinical trials

 

2. Clinical trial outcome measures

 

3. Clinical trial inclusion/exclusion criteria and ethics

 

4. Clinical trial design

 


 

 

 

 

 

 

 

 

 

 

 

 

 

 
 
Copyright 2014 University of Miami. All rights reserved.